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Pen-Hui Yin Selected Research

Mitochondrial DNA (mtDNA)

11/2016Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway.
10/2013Mitochondrial dysfunction represses HIF-1α protein synthesis through AMPK activation in human hepatoma HepG2 cells.
10/2011Somatic mutations of the mitochondrial genome in human breast cancers.
5/2010Mitochondrial DNA content as a potential marker to predict response to anthracycline in breast cancer patients.
3/2010Somatic mutations in mitochondrial genome and their potential roles in the progression of human gastric cancer.
3/2010Somatic mutations of mitochondrial genome in hepatocellular carcinoma.
5/2009Association between mitochondrial DNA 4,977 bp deletion and NAD(P)H:quinone oxidoreductase 1 C609T polymorphism in human breast tissues.
3/2008Tandem duplication/triplication correlated with poly-cytosine stretch variation in human mitochondrial DNA D-loop region.
2/2007Heteroplasmic mutation of mitochondrial DNA D-loop and 4977-bp deletion in human cancer cells during mitochondrial DNA depletion.
7/2006Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer.
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Pen-Hui Yin Research Topics

Disease

21Neoplasms (Cancer)
12/2017 - 05/2002
9Stomach Neoplasms (Stomach Cancer)
10/2018 - 05/2005
8Hepatocellular Carcinoma (Hepatoma)
09/2015 - 05/2002
7Breast Neoplasms (Breast Cancer)
01/2016 - 07/2006
6Mitochondrial Diseases (Mitochondrial Disease)
10/2018 - 03/2010
4Neoplasm Metastasis (Metastasis)
07/2018 - 12/2009
4Carcinogenesis
04/2014 - 05/2005
2Papillary Thyroid Cancer
11/2011 - 06/2010
1Starvation
12/2017
1Triple Negative Breast Neoplasms
12/2017
1Diabetes Mellitus
09/2015
1Hypoxia (Hypoxemia)
10/2013
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2013
1Blister (Bulla)
01/2013
1Lymphatic Metastasis
11/2011
1Thyroid Neoplasms (Thyroid Cancer)
06/2010
1Colonic Neoplasms (Colon Cancer)
02/2007
1Carcinoma (Carcinomatosis)
09/2005
1Lung Neoplasms (Lung Cancer)
05/2005
1Colorectal Neoplasms (Colorectal Cancer)
05/2005

Drug/Important Bio-Agent (IBA)

12Mitochondrial DNA (mtDNA)IBA
11/2016 - 05/2005
5Proteins (Proteins, Gene)FDA Link
10/2018 - 12/2011
4Cisplatin (Platino)FDA LinkGeneric
10/2018 - 03/2010
3Glutathione (Reduced Glutathione)IBA
10/2018 - 11/2016
3Reactive Oxygen Species (Oxygen Radicals)IBA
10/2018 - 07/2012
3OligomycinsIBA
11/2016 - 03/2010
2Cystine (L-Cystine)IBA
10/2018 - 12/2017
2EnzymesIBA
11/2016 - 05/2009
2Cadherins (E-Cadherin)IBA
01/2016 - 12/2009
2Biomarkers (Surrogate Marker)IBA
04/2014 - 05/2010
2NAD (NADH)IBA
04/2014 - 05/2009
2LeptinIBA
11/2011 - 06/2010
2Leptin ReceptorsIBA
11/2011 - 06/2010
2Ethidium (Ethidium Bromide)IBA
05/2010 - 02/2007
2GlucocorticoidsIBA
12/2008 - 05/2002
2Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
12/2008 - 05/2002
2Estrogens (Estrogen)FDA Link
12/2008 - 08/2004
2Poly CIBA
03/2008 - 02/2007
2NucleotidesIBA
03/2008 - 09/2005
1Heme Oxygenase-1IBA
10/2018
1salubrinalIBA
10/2018
1Glutamic Acid (Glutamate)FDA Link
10/2018
1PhosphoenolpyruvateIBA
10/2018
1Peptide Initiation Factors (Initiation Factor)IBA
10/2018
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
07/2018
1LigandsIBA
07/2018
1Chelating AgentsIBA
12/2017
1Amino AcidsFDA Link
12/2017
1NecroX-5IBA
12/2017
1ferrostatin-1IBA
12/2017
16- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA
12/2017
1N- (4- (N- (3- methoxypyrazin- 2- yl)sulfamoyl)phenyl)- 3- (5- nitrothiophene- 2- yl)acrylamideIBA
12/2017
1necrostatin-1IBA
12/2017
1Deferoxamine (Desferal)FDA LinkGeneric
12/2017
1Serine (L-Serine)FDA Link
12/2017
1Cysteine (L-Cysteine)FDA Link
12/2017
1Small Interfering RNA (siRNA)IBA
11/2016
1Phosphotransferases (Kinase)IBA
11/2016
13' Untranslated Regions (3' UTR)IBA
01/2016
1MicroRNAs (MicroRNA)IBA
01/2016
1Basic Helix-Loop-Helix Transcription FactorsIBA
01/2016
1BiguanidesIBA
09/2015
1SirtuinsIBA
04/2014
1Sirtuin 3IBA
04/2014
1Transcription Factors (Transcription Factor)IBA
10/2013
1Adenosine Triphosphate (ATP)IBA
10/2013
1Messenger RNA (mRNA)IBA
10/2013
1Zoledronic Acid (Zometa)FDA Link
09/2013
1norcantharidinIBA
01/2013
1Cantharidin (Cantharides)IBA
01/2013
1ErbB Receptors (EGF Receptor)IBA
01/2013
1Gefitinib (Iressa)FDA Link
01/2013
1Antimycin AIBA
07/2012
1Neutralizing AntibodiesIBA
07/2012
1rab5 GTP-Binding ProteinsIBA
12/2011
1CytokinesIBA
11/2011
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
11/2011
1Hormones (Hormone)IBA
06/2010
1AnthracyclinesIBA
05/2010
1Val Transfer RNAIBA
03/2010
1DNA (Deoxyribonucleic Acid)IBA
03/2010
1Ala Transfer RNAIBA
03/2010
1PPAR gammaIBA
12/2009
1Oxidoreductases (Dehydrogenase)IBA
05/2009
1quinone (benzoquinone)IBA
05/2009
1CaspasesIBA
12/2008
1Dexamethasone (Maxidex)FDA LinkGeneric
12/2008
1Annexin A5IBA
12/2008
1Lactic Acid (Lactate)FDA LinkGeneric
12/2008
12-MethoxyestradiolIBA
12/2008
1Caspase 8 (Caspase-8)IBA
12/2008
1peroxisome-proliferator-activated receptor-gamma coactivator-1IBA
03/2008
1CytosineIBA
03/2008
1CytidineIBA
02/2007
1Indicators and Reagents (Reagents)IBA
07/2006
1Progesterone Receptors (Progesterone Receptor)IBA
07/2006
1Estrogen ReceptorsIBA
07/2006
1Hydrocortisone (Cortisol)FDA LinkGeneric
05/2002

Therapy/Procedure

2Therapeutics
07/2018 - 11/2016
1Adjuvant Chemotherapy
11/2016